Daily Archives: October 2, 2025

Senators Cruz and Cornyn Want To Steal Space Shuttle Discovery from Smithsonian and Chop it Up to Move it.

Posted on by

Keith’s note: I just got an update from KeepTheShuttle. OMB wants NASA and the Smithsonian to figure out how to cut Space Shuttle Discovery apart into pieces to move it. As you will recall that option was ruled out when Space Shuttle Endeavour was moved to Los Angeles on the now-defunct 747 carrier and then moved through the streets where utilities were moved and trees were cut down. Every effort was taken to preserve the integrity of this historic space ship. Now Texas Senators Ted Cruz and John Cornyn are only interested in snagging a tourist attraction – not a precious historic relic that deserves to be preserved – and certainly not chopped up like a leftover exhibit from a state fair and tossed on a flatbed. Full statement below.

[…]

This development is unprecedented and alarming. NASA did not design the shuttle orbiters to be disassembled, and complicating factors include the shuttle’s aluminum frame, ~24,000 delicate ceramic tiles that coat the shuttle’s underside (the black part), and ~2,000 thermal insulation fabric blankets that coat the rest of the shuttle (the white part). Disassembling Discovery would cause significant and irreparable damage to these and other portions of the shuttle.

Discovery also holds particular value, as the shuttle was specially preserved to serve as a future reference for researchers. To quote Dennis Jenkins, who was the director of NASA’s program to retire the shuttle fleet “We spent a lot of time and money to preserve Discovery in as near to flight condition as we could to put it in the national collection, so that any future engineer or historian has a reference vehicle to look at, measure or do whatever they need”. The process that the White House is now asking the Smithsonian and NASA to explore would permanently ruin this work and significantly hamper the ability of future generations to study and learn from Discovery.

The letter also references that NASA and the Smithsonian are in agreement that the cost to move Discovery to Houston would, at minimum, be between $120 million and $150 million, exclusive of the cost of building a new exhibit in Houston. This number significantly exceeds the $85 million authorized for the relocation and a new exhibit by the OBBBA, and indicates that additional taxpayer funding will be necessary. A

[…]

Letter from the Smithsonian to Congressional Authorizing & Appropriating Committees:

“The Smithsonian has been asked by OMB to work with NASA to prepare to move the Discovery space shuttle to Houston, TX, within the 18 months specified in the reconciliation bill signed into law on July 4, 2025. The bill does not specifically mention Discovery as the designated vehicle for relocation, and its terms could include any number of space vehicles, but the administration is interpreting the law as sufficiently specific to move forward with the transfer of Discovery. The Smithsonian and NASA have been asked to begin by verifying the actual costs associated with the move.

While an engineering study will be necessary due to the size and weight of the space vehicle, both NASA and the Smithsonian believe that Discovery will have to undergo significant disassembly to be moved.

[…]

NASA transferred “all rights, title, interest and ownership” of the shuttle to the Smithsonian. We remain concerned about the unprecedented nature of a removal of an object from the national collection, and that we would be causing damage to the most intact orbiter from the space shuttle program

[…]

Source: Senators Cruz and Cornyn Want To Chop Up Space Shuttle Discovery – NASA Watch

Entangled states enhance energy transfer in models of molecular systems

Posted on by

A study from Rice University, published in PRX Quantum, has found that energy transfers more quickly between molecular sites when it starts in an entangled, delocalized quantum state instead of from a single site. The discovery could lead to the development of more efficient light-harvesting materials that enhance the conversion of energy from light into other forms of energy.

Many , including photosynthesis, depend on rapid and efficient energy transfer following absorption. Understanding how quantum mechanical effects like entanglement influence these processes at room temperature could significantly change our approach to creating artificial systems that mimic nature’s efficiency.

“Delocalizing the initial excitation across multiple sites accelerates the transfer in ways that starting from a single site cannot achieve,” said Guido Pagano, the study’s corresponding author and assistant professor of physics and astronomy.

Model and method

The study uses a simplified model molecule consisting of two regions: a donor, where energy is initially absorbed, and an acceptor, where the energy must eventually arrive. Energy can hop between sites within each region; although longer hops are less likely, they are still included in the model. The model also accounts for interactions with the environment, which can couple with the molecule’s vibrations and affect the energy transfer process.

A key focus of the research was determining whether it is more effective for energy to start entirely at one donor site or in a delocalized or entangled superposition spread over two or more donor sites. The researchers explored whether this quantum mechanical property impacts transfer speed in a system with long-range interactions.

“Starting in a delocalized provides the system with more pathways,” Pagano said. “Our simulations indicate that this added coherence allows for quicker transfer to the acceptor, even in the presence of environmental noise.”

Findings and implications

The research team discovered that when energy begins in an entangled initial state, transfer to the acceptor occurs significantly faster than in scenarios where the energy starts at a single site. This finding holds true across various model parameters, including the strength of environmental coupling, the range of interactions between sites and disorder within the system.

“This suggests that nature may be using entanglement and coherence to optimize the speed of excitation transfer, thereby enhancing the robustness of this process,” Pagano said.

Although the model is intentionally minimal, the researchers argue that its implications extend to more complex molecular systems. They propose that could be conducted using controllable quantum platforms such as trapped-ion systems to simulate the physics of molecular energy transfer.

“Our goal is to bridge the abstract world of quantum information with the tangible mechanisms observed in biology,” said Diego Fallas Padilla, the study’s first author and Rice alumnus. “This study serves as a step toward illustrating that quantum coherence is not just a theoretical curiosity but a practical component of nature’s design.”

Co-authors of the study include Rice’s Visal So, Abhishek Menon, Roman Zhuravel and Han Pu.

More information: Diego Fallas Padilla et al, Delocalized Excitation Transfer in Open Quantum Systems with Long-Range Interactions, PRX Quantum (2025). DOI: 10.1103/bxwl-sbsn

Journal information: PRX Quantum

Provided by Rice University

Source: Entangled states enhance energy transfer in models of molecular systems

A common supplement could supercharge cancer treatments

Posted on by

In a new study, researchers from the University of Chicago discovered that zeaxanthin, a plant-derived carotenoid best known for protecting vision, may also act as an immune-boosting compound by strengthening the cancer-fighting activity of immune cells. The findings, which were published in Cell Reports Medicine, highlight the potential of zeaxanthin as a widely available supplement to improve the effectiveness of cancer immunotherapies.

“We were surprised to find that zeaxanthin, already known for its role in eye health, has a completely new function in boosting anti-tumor immunity,” said Jing Chen, PhD, Janet Davison Rowley Distinguished Service Professor of Medicine and senior author of the study. “Our study show that a simple dietary nutrient could complement and strengthen advanced cancer treatments like immunotherapy.”

How does this nutrient work?

The study builds on years of work by Chen’s lab to better understand how nutrients influence the immune system. By screening a large blood nutrient library, the team identified zeaxanthin as a compound that directly enhances the activity of CD8+ T cells, a crucial type of immune cell that kills tumor cells. These cells rely on a molecular structure called the T-cell receptor (TCR) to recognize and destroy abnormal cells.

The researchers found that zeaxanthin stabilizes and strengthens the formation of TCR complex on CD8+ T cells upon interacting with the cancer cells. This, in turn, triggers more robust intracellular signaling that boosts T-cell activation, cytokine production, and tumor-killing capacity.

Zeaxanthin improves immunotherapy effects

In mouse models, dietary supplementation with zeaxanthin slowed tumor growth. Importantly, when combined with immune checkpoint inhibitors – a type of immunotherapy that has transformed cancer treatment in recent years – zeaxanthin significantly enhanced anti-tumor effects compared to immunotherapy alone.

To extend the findings, the researchers tested human T cells engineered to recognize specific tumor antigens and found that zeaxanthin treatment improved these cells’ ability to kill melanoma, multiple myeloma, and glioblastoma cells in laboratory experiments.

[…]

`

Zeaxanthin is sold as an over-the-counter supplement for eye health, and is naturally found in vegetables like orange peppers, spinach, and kale. It’s inexpensive, widely available, well-tolerated and, most importantly, its safety profile is known – which means it can be safely tested as an adjunct to cancer therapies.

The study also reinforces the importance of a balanced diet. In their previous research, Chen’s group discovered that trans-vaccenic acid (TVA), a fatty acid derived from dairy and meat, also boosts T-cell activity – but through a different mechanism. Together, the findings suggest that nutrients from both plant and animal sources may provide complementary benefits to immune health.

Clinical applications of zeaxanthin

Although the results are promising, the researchers emphasize that the work is still at an early stage. Most of the findings come from laboratory experiments and animal studies. Thus, clinical trials will be needed to determine whether zeaxanthin supplements can improve outcomes for cancer patients.

[…]

Source: A common supplement could supercharge cancer treatments | ScienceDaily