WHO Reccomends cheap malaria vaccine

The vaccine has been developed by the University of Oxford and is only the second malaria vaccine to be developed.

Malaria kills mostly babies and infants, and has been one of the biggest scourges on humanity.

There are already agreements in place to manufacture more than 100 million doses a year.

It has taken more than a century of scientific effort to develop effective vaccines against malaria.

The disease is caused by a complex parasite, which is spread by the bite of blood-sucking mosquitoes. It is far more sophisticated than a virus as it hides from our immune system by constantly shape-shifting inside the human body.

[…]

The WHO said the effectiveness of the two vaccines was “very similar” and there was no evidence one was better than the other.

However, the key difference is the ability to manufacture the University of Oxford vaccine – called R21 – at scale.

The world’s largest vaccine manufacturer – the Serum Institute of India – is already lined up to make more than 100 million doses a year and plans to scale up to 200 million doses a year.

So far there are only 18 million doses of RTS,S.

The WHO said the new R21 vaccine would be a “vital additional tool”. Each dose costs $2-4 (£1.65 to £3.30) and four doses are needed per person. That is about half the price of RTS,S.

[…]

That makes it hard to build up immunity naturally through catching malaria, and difficult to develop a vaccine against it.

It is almost two years to the day since the first vaccine – called RTS,S and developed by GSK – was backed by the WHO.

Source: Malaria vaccine big advance against major child killer – BBC News

Adobe previews AI upscaling to make blurry videos and GIFs look fresh

Adobe has developed an experimental AI-powered upscaling tool that greatly improves the quality of low-resolution GIFs and video footage. This isn’t a fully-fledged app or feature yet, and it’s not yet available for beta testing, but if the demonstrations seen by The Verge are anything to go by then it has some serious potential.

Adobe’s “Project Res-Up” uses diffusion-based upsampling technology (a class of generative AI that generates new data based on the data it’s trained on) to increase video resolution while simultaneously improving sharpness and detail.

In a side-by-side comparison that shows how the tool can upscale video resolution, Adobe took a clip from The Red House (1947) and upscaled it from 480 x 360 to 1280 x 960, increasing the total pixel count by 675 percent. The resulting footage was much sharper, with the AI removing most of the blurriness and even adding in new details like hair strands and highlights. The results still carried a slightly unnatural look (as many AI video and images do) but given the low initial video quality, it’s still an impressive leap compared to the upscaling on Nvidia’s TV Shield or Microsoft’s Video Super Resolution.

The footage below provided by Adobe matches what I saw in the live demonstration:

A clip from a black and white movie called The Red House (1947) featuring a young man and woman.
[Left: original, Right: upscaled] Running this clip from The Red House (1947) through Project Res-Up removes most of the blur and makes details like the character’s hair and eyes much sharper.Image: The Red House (1947) / United Artists / Adobe

Another demonstration showed a video being cropped to focus on a baby elephant, with the upscaling tool similarly boosting the low-resolution crop and eradicating most of the blur while also adding little details like skin wrinkles. It really does look as though the tool is sharpening low-contrast details that can’t be seen in the original footage. Impressively, the artificial wrinkles move naturally with the animal without looking overly artificial. Adobe also showed Project Res-Up upscaling GIFs to breathe some new life into memes you haven’t used since the days of MySpace.

A side-by-side comparison of baby elephant video footage.
[Left: original, Right: upscaled] Additional texture has been applied to this baby elephant to make the upscaled footage appear more natural and lifelike.Image: Adobe

The project will be revealed during the “Sneaks” section of the Adobe Max event later today, which the creative software giant uses to showcase future technologies and ideas that could potentially join Adobe’s product lineup. That means you won’t be able to try out Project Res-Up on your old family videos (yet) but its capabilities could eventually make their way into popular editing apps like Adobe Premiere Pro or Express. Previous Adobe Sneaks have since been released as apps and features, like Adobe Fresco and Photoshop’s content-aware tool.

Source: Adobe previews AI upscaling to make blurry videos and GIFs look fresh – The Verge