evidence of transgenerational epigenetic inheritance: ‘Memories’ pass between generations

Experiments showed that a traumatic event could affect the DNA in sperm and alter the brains and behaviour of subsequent generations. A Nature Neuroscience study shows mice trained to avoid a smell passed their aversion on to their “grandchildren”. The animals were trained to fear a smell similar to cherry blossom. The team at the Emory University School of Medicine, in the US, then looked at what was happening inside the sperm. They showed a section of DNA responsible for sensitivity to the cherry blossom scent was made more active in the mice’s sperm. Both the mice’s offspring, and their offspring, were “extremely sensitive” to cherry blossom and would avoid the scent, despite never having experiencing it in their lives. hanges in brain structure were also found. “The experiences of a parent, even before conceiving, markedly influence both structure and function in the nervous system of subsequent generations,” the report concluded.

The findings provide evidence of “transgenerational epigenetic inheritance” – that the environment can affect an individual’s genetics, which can in turn be passed on.

via BBC News – ‘Memories’ pass between generations.

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